Make up wipes do not clean the face thoroughly and usually leave some residue behind. They do move dirt around the face, however as a last resort they can be used occasionally when one is tired or travelling as it is better than leaving the make up on.
Should toothpaste be used? why not. It is cost effective , available everywhere in plenty and in all seasons and is highly effective. However in case of acne, for a single acne one could apply it with a toothpick on acne itself. But use liberally it can dry out and irritate the skin. Chronic severe acne must not be allowed to be treated by toothpaste and must be consulted by dermatologist at earliest.
Despite all precautionary measures, you are most likely to end up being all green, pink and blue by the afternoon. While spending hours scrubbing off the Holi hues are part of the festive fun, make sure you use the right ingredients to do so.